| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 4 |
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| Ligand | BDBM50049395 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1775382 (CHEMBL4232374) |
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| IC50 | 490±n/a nM |
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| Citation |  Li, N; Wang, LJ; Jiang, B; Li, XQ; Guo, CL; Guo, SJ; Shi, DY Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus. Eur J Med Chem151:145-157 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 4 |
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| Name: | Dipeptidyl peptidase 4 |
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| Synonyms: | CD26 | CD_antigen=CD26 | DPP IV | DPP4 | DPP4_PIG | Dipeptidyl peptidase 4 | Dipeptidyl peptidase 4 membrane form | Dipeptidyl peptidase 4 soluble form | Dipeptidyl peptidase IV | Dipeptidyl peptidase IV membrane form | Dipeptidyl peptidase IV soluble form | T-cell activation antigen CD26 |
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| Type: | Enzyme |
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| Mol. Mass.: | 88235.21 |
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| Organism: | Sus scrofa (pig) |
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| Description: | n/a |
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| Residue: | 766 |
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| Sequence: | MKTPWKVLLGLLGIAALVTVITVPVVLLNKGTDDAAADSRRTYTLTDYLKSTFRVKFYTL
QWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDELGYSTNDYSVSPDRQFILFEYNY
VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWSPVGHKLAYVWNNDIYVKNEPNL
SSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF
YSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSPNASVTSYQIVPPASVLIGDHYL
CGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWISSVARQHIEISTTGWVGRFRPA
EPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFITKGAWEVIGIEALTSDYLYYISN
EHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQYYSASFSNKAKYYQLRCFGPGLPLY
TLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDVINLHGTKFWYQMILPPHFDKSKKY
PLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT
FEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVTSMVLGAGSGVFKCGIAVAPVSKWE
YYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQLS
KALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMSHFLKQCFSLP
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| BDBM50049395 |
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| n/a |
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| Name | BDBM50049395 |
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| Synonyms: | 5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one | 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one | 6-methoxy apigenin | 6-methoxyapigenin | CHEMBL293776 | Hispidulin | NSC-122415 | TCMDC-123942 | cid_5281628 | dinatin |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12O6 |
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| Mol. Mass. | 300.2629 |
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| SMILES | COc1c(O)cc2oc(cc(=O)c2c1O)-c1ccc(O)cc1 |
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| Structure | 
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