| Reaction Details |
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 | Report a problem with these data |
| Target | Oxoeicosanoid receptor 1 |
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| Ligand | BDBM50465686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1785336 (CHEMBL4256853) |
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| IC50 | 120±n/a nM |
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| Citation |  Chourey, S; Ye, Q; Reddy, CN; Wang, R; Cossette, C; Gravel, S; Slobodchikova, I; Vuckovic, D; Rokach, J; Powell, WS Novel Highly Potent and Metabolically Resistant Oxoeicosanoid (OXE) Receptor Antagonists That Block the Actions of the Granulocyte Chemoattractant 5-Oxo-6,8,11,14-Eicosatetraenoic Acid (5-oxo-ETE). J Med Chem61:5934-5948 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxoeicosanoid receptor 1 |
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| Name: | Oxoeicosanoid receptor 1 |
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| Synonyms: | 5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45833.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | TG 1019 0 HUMAN::Q8TDS5 |
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| Residue: | 423 |
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| Sequence: | MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPS
FSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIH
TRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASV
VFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSY
RVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMV
VAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSP
NFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGS
SQG
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| BDBM50465686 |
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| n/a |
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| Name | BDBM50465686 |
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| Synonyms: | CHEMBL4277207 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32ClNO4 |
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| Mol. Mass. | 470 |
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| SMILES | C[C@@H](CC(O)=O)CC(=O)c1c([C@@H](O)CCCCCc2ccccc2)n(C)c2ccc(Cl)cc12 |r| |
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| Structure | 
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