| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-1 |
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| Ligand | BDBM50465984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1789504 (CHEMBL4261238) |
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| Ki | 53±n/a nM |
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| Citation |  Guo, T; Héon-Roberts, R; Zou, C; Zheng, R; Pshezhetsky, AV; Cairo, CW Selective Inhibitors of Human Neuraminidase 1 (NEU1). J Med Chem61:11261-11279 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-1 |
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| Name: | Sialidase-1 |
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| Synonyms: | NANH | NEU1 | NEUR1_HUMAN | Sialidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45463.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960639 |
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| Residue: | 415 |
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| Sequence: | MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
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| BDBM50465984 |
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| n/a |
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| Name | BDBM50465984 |
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| Synonyms: | CHEMBL4278858 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23N5O8 |
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| Mol. Mass. | 449.4146 |
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| SMILES | [H][C@]1(OC(=C[C@H](O)[C@H]1NC(=O)Cn1cc(nn1)-c1ccc(N)cc1)C(O)=O)[C@H](O)[C@H](O)CO |r,c:3| |
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| Structure | 
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