| Reaction Details |
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 | Report a problem with these data |
| Target | Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase |
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| Ligand | BDBM50466402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1793118 (CHEMBL4265037) |
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| IC50 | >1000000±n/a nM |
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| Citation |  DiFrancesco, BR; Morrison, ZA; Nitz, M Monosaccharide inhibitors targeting carbohydrate esterase family 4 de-N-acetylases. Bioorg Med Chem26:5631-5643 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase |
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| Name: | Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase |
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| Synonyms: | PGAB_ECOLI | PNAG de-N-acetylase (PgaB) | pgaB | ycdR |
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| Type: | Protein |
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| Mol. Mass.: | 77407.78 |
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| Organism: | Escherichia coli (Enterobacteria) |
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| Description: | P75906 |
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| Residue: | 672 |
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| Sequence: | MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPWPHNGFVAISWHNVEDE
AADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGKPLPEKAVVLTFDDGYQSF
YTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVDREYFATWQQVREVARSRLVE
LASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYETAAEYRERIRLDAVKMTEYLRTK
VEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLESGLANASQLDSIPRVLIANNPSLKE
FAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDRNIDVLIQRVKDMQISTVYLQAFADPD
GDGLVKEVWFPNRLLPMKADIFSRVAWQLRTRSGVNIYAWMPVLSWDLDPTLTRVKYLPT
GEKKAQIHPEQYHRLSPFDDRVRAQVGMLYEDLAGHAAFDGILFHDDALLSDYEDASAPA
ITAYQQAGFSGSLSEIRQNPEQFKQWARFKSRALTDFTLELSARVKAIRGPHIKTARNIF
ALPVIQPESEAWFAQNYADFLKSYDWTAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQA
KDKSILELQAQNWQKNGQHQAISSQQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIR
PEFSTAWYPKND
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| BDBM50466402 |
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| n/a |
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| Name | BDBM50466402 |
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| Synonyms: | CHEMBL4291068 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21NO6S2 |
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| Mol. Mass. | 363.45 |
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| SMILES | CS(=O)(=O)N[C@@H]1[C@@H](S)[C@H](O)[C@@H](CO)O[C@H]1OCc1ccccc1 |r| |
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| Structure | 
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