| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dopamine beta-hydroxylase |
|---|
| Ligand | BDBM50026182 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_59141 |
|---|
| Ki | 21000±n/a nM |
|---|
| Citation |  Bargar, TM; Broersma, RJ; Creemer, LC; McCarthy, JR; Hornsperger, JM; Palfreyman, MG; Wagner, J; Jung, MJ Unsaturated heterocyclic amines as potent time-dependent inhibitors of dopamine beta-hydroxylase. J Med Chem29:315-7 (1986) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dopamine beta-hydroxylase |
|---|
| Name: | Dopamine beta-hydroxylase |
|---|
| Synonyms: | DBH | DOPO_BOVIN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 68136.39 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_50738 |
|---|
| Residue: | 610 |
|---|
| Sequence: | MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISY
AQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDS
QQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSG
LHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIV
MYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAK
AFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMEL
GLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARD
GRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEM
CVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSF
NREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGP
TVLNISGGKG
|
|
|
|---|
| BDBM50026182 |
|---|
| n/a |
|---|
| Name | BDBM50026182 |
|---|
| Synonyms: | 3-Phenyl-prop-2-ynylamine | CHEMBL110611 | US9161922, Table 1, Compound 3 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H9N |
|---|
| Mol. Mass. | 131.1745 |
|---|
| SMILES | NCC#Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
