| Reaction Details |
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 | Report a problem with these data |
| Target | Dopamine beta-hydroxylase |
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| Ligand | BDBM50026187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_59141 |
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| Ki | 410000±n/a nM |
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| Citation |  Bargar, TM; Broersma, RJ; Creemer, LC; McCarthy, JR; Hornsperger, JM; Palfreyman, MG; Wagner, J; Jung, MJ Unsaturated heterocyclic amines as potent time-dependent inhibitors of dopamine beta-hydroxylase. J Med Chem29:315-7 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Dopamine beta-hydroxylase |
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| Name: | Dopamine beta-hydroxylase |
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| Synonyms: | DBH | DOPO_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68136.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_50738 |
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| Residue: | 610 |
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| Sequence: | MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISY
AQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDS
QQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSG
LHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIV
MYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAK
AFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMEL
GLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARD
GRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEM
CVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSF
NREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGP
TVLNISGGKG
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|
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| BDBM50026187 |
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| n/a |
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| Name | BDBM50026187 |
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| Synonyms: | 2-Furan-2-yl-allylamine | CHEMBL106238 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H9NO |
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| Mol. Mass. | 123.1525 |
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| SMILES | NCC(=C)c1ccco1 |
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| Structure | 
|
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