| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
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| Ligand | BDBM50469778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_43103 (CHEMBL657560) |
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| IC50 | >100000±n/a nM |
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| Citation |  Velentza, AV; Wainwright, MS; Zasadzki, M; Mirzoeva, S; Schumacher, AM; Haiech, J; Focia, PJ; Egli, M; Watterson, DM An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury. Bioorg Med Chem Lett13:3465-70 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type II subunit gamma |
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| Name: | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
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| Synonyms: | 2.7.11.17 | CAMK | CAMK-II | CAMK2G | CAMKG | CaM kinase II | CaM kinase II gamma | CaM kinase II subunit gamma | CaMK-II subunit gamma | Calcium/calmodulin-dependent protein kinase type II subunit gamma | Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMKllg) | KCC2G_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 62621.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13555 |
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| Residue: | 558 |
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| Sequence: | MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
KGAILTTMLVSRNFSAAKSLLNKKSDGGVKKRKSSSSVHLMPQSNNKNSLVSPAQEPAPL
QTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKGRVPEGRSSRDRTAPSAGMQPQPSL
CSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFE
NLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDG
KWLNVHYHCSGAPAAPLQ
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| BDBM50469778 |
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| n/a |
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| Name | BDBM50469778 |
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| Synonyms: | CHEMBL116963 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H36N6O |
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| Mol. Mass. | 508.6571 |
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| SMILES | N=c1ccc(nn1CCCCCCCCCCC(=O)Nc1ccc(nn1)-c1ccccc1)-c1ccccc1 |
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| Structure | 
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