| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50469877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1667 (CHEMBL616658) |
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| Ki | 32±n/a nM |
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| Citation |  Clitherow, JW; Scopes, DI; Skingle, M; Jordan, CC; Feniuk, W; Campbell, IB; Carter, MC; Collington, EW; Connor, HE; Higgins, GA Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. J Med Chem37:2253-7 (1994) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41780.38 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
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| Residue: | 376 |
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| Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
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| BDBM50469877 |
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| n/a |
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| Name | BDBM50469877 |
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| Synonyms: | CHEMBL72092 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N2O4 |
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| Mol. Mass. | 446.5381 |
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| SMILES | COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccc(cc1C)C(O)=O |
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| Structure | 
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