Reaction Details |
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Target | 5-hydroxytryptamine receptor 1D |
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Ligand | BDBM50469879 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1667 (CHEMBL616658) |
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Ki | 3.2±n/a nM |
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Citation | Clitherow, JW; Scopes, DI; Skingle, M; Jordan, CC; Feniuk, W; Campbell, IB; Carter, MC; Collington, EW; Connor, HE; Higgins, GA Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. J Med Chem37:2253-7 (1994) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 1D |
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Name: | 5-hydroxytryptamine receptor 1D |
Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 41780.38 |
Organism: | GUINEA PIG |
Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
Residue: | 376 |
Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
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BDBM50469879 |
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n/a |
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Name | BDBM50469879 |
Synonyms: | CHEMBL72088 |
Type | Small organic molecule |
Emp. Form. | C24H26N4O2 |
Mol. Mass. | 402.4888 |
SMILES | COc1ccc(cc1N1CCN(C)CC1)C(=O)Nc1ccc(cc1)-c1ccncc1 |
Structure |
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