Reaction Details |
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Target | 5-hydroxytryptamine receptor 1D |
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Ligand | BDBM50469882 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1667 (CHEMBL616658) |
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Ki | 3.2±n/a nM |
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Citation | Clitherow, JW; Scopes, DI; Skingle, M; Jordan, CC; Feniuk, W; Campbell, IB; Carter, MC; Collington, EW; Connor, HE; Higgins, GA Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. J Med Chem37:2253-7 (1994) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 1D |
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Name: | 5-hydroxytryptamine receptor 1D |
Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 41780.38 |
Organism: | GUINEA PIG |
Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
Residue: | 376 |
Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
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BDBM50469882 |
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n/a |
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Name | BDBM50469882 |
Synonyms: | CHEMBL73446 |
Type | Small organic molecule |
Emp. Form. | C30H36N2O5 |
Mol. Mass. | 504.6172 |
SMILES | COCCOC(=O)c1ccc(c(C)c1)-c1ccc(NC(=O)c2ccc(OC)c(CCCN(C)C)c2)cc1 |
Structure |
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