| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50321869 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2526 (CHEMBL616876) |
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| Ki | 158±n/a nM |
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| Citation |  Bromidge, SM; Dabbs, S; Davies, DT; Duckworth, DM; Forbes, IT; Ham, P; Jones, GE; King, FD; Saunders, DV; Starr, S; Thewlis, KM; Wyman, PA; Blaney, FE; Naylor, CB; Bailey, F; Blackburn, TP; Holland, V; Kennett, GA; Riley, GJ; Wood, MD Novel and selective 5-HT2C/2B receptor antagonists as potential anxiolytic agents: synthesis, quantitative structure-activity relationships, and molecular modeling of substituted 1-(3-pyridylcarbamoyl)indolines. J Med Chem41:1598-612 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50321869 |
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| n/a |
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| Name | BDBM50321869 |
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| Synonyms: | 6-Chloro-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide | 6-chloro-5-methyl-N-(pyridin-3-yl)indoline-1-carboxamide | CHEMBL42024 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14ClN3O |
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| Mol. Mass. | 287.744 |
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| SMILES | Cc1cc2CCN(C(=O)Nc3cccnc3)c2cc1Cl |
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| Structure | 
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