| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM30130 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_33479 (CHEMBL649810) |
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| Ki | 6.3±n/a nM |
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| Citation |  Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties. J Med Chem44:787-805 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 48979.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08913 |
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| Residue: | 465 |
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| Sequence: | MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM30130 |
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| n/a |
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| Name | BDBM30130 |
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| Synonyms: | CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine | Prozac | US9120771, Fluoxetine | cid_62857 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18F3NO |
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| Mol. Mass. | 309.3261 |
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| SMILES | CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 |
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| Structure | 
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