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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mitogen-activated protein kinase 13 | ||
| Ligand | BDBM50473629 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_124318 (CHEMBL732626) | ||
| IC50 | 4.0±n/a nM | ||
| Citation |  McKenna, JM; Halley, F; Souness, JE; McLay, IM; Pickett, SD; Collis, AJ; Page, K; Ahmed, I An algorithm-directed two-component library synthesized via solid-phase methodology yielding potent and orally bioavailable p38 MAP kinase inhibitors. J Med Chem45:2173-84 (2002) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mitogen-activated protein kinase 13 | |||
| Name: | Mitogen-activated protein kinase 13 | ||
| Synonyms: | MAP kinase 13 | MAP kinase p38 delta | MAPK 13 | MK13_MOUSE | Mapk13 | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase p38 delta | Serk4 | Stress-activated protein kinase 4 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 42081.17 | ||
| Organism: | Mus musculus | ||
| Description: | ChEMBL_105000 | ||
| Residue: | 366 | ||
| Sequence: |
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| BDBM50473629 | |||
| n/a | |||
| Name | BDBM50473629 | ||
| Synonyms: | CHEMBL70053 | RPR-238677 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H34FN7O3 | ||
| Mol. Mass. | 535.6131 | ||
| SMILES | CN1CCN(CC1)C(=O)[C@@]1(C)CO[C@@H](OC1)c1nc(c([nH]1)-c1ccnc(NCC2CC2)n1)-c1ccc(F)cc1 |wU:13.17,9.10,wD:9.9,(22.52,-6.15,;20.98,-6.15,;20.21,-4.81,;18.66,-4.8,;17.9,-6.13,;18.65,-7.46,;20.19,-7.48,;16.36,-6.13,;15.59,-7.46,;15.6,-4.8,;16.36,-3.46,;14.84,-3.46,;13.3,-3.46,;12.54,-4.79,;13.3,-6.12,;14.83,-6.12,;11,-4.79,;10.07,-6.03,;8.62,-5.54,;8.63,-4,;10.1,-3.53,;7.3,-3.23,;7.3,-1.68,;5.96,-.91,;4.62,-1.68,;4.62,-3.23,;3.28,-4,;1.95,-3.23,;.62,-4,;-.16,-5.33,;-.93,-4,;5.96,-4,;7.37,-6.45,;5.96,-5.8,;4.72,-6.7,;4.87,-8.25,;3.53,-9,;6.29,-8.88,;7.53,-7.97,)| | ||
| Structure | 
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