| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM50413272 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_326476 (CHEMBL864468) |
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| EC50 | 10.0±n/a nM |
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| Citation |  Lund, BW; Piu, F; Gauthier, NK; Eeg, A; Currier, E; Sherbukhin, V; Brann, MR; Hacksell, U; Olsson, R Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem48:7517-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50498.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458015 |
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| Residue: | 455 |
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| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
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| BDBM50413272 |
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| n/a |
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| Name | BDBM50413272 |
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| Synonyms: | AC-261066 | CHEMBL198997 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20FNO4S |
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| Mol. Mass. | 353.408 |
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| SMILES | CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1 |
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| Structure | 
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