| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase |
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| Ligand | BDBM50475564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_327334 (CHEMBL865149) |
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| IC50 | 390±n/a nM |
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| Citation |  Marson, CM; Savy, P; Rioja, AS; Mahadevan, T; Mikol, C; Veerupillai, A; Nsubuga, E; Chahwan, A; Joel, SP Aromatic sulfide inhibitors of histone deacetylase based on arylsulfinyl-2,4-hexadienoic acid hydroxyamides. J Med Chem49:800-5 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase |
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| Name: | Histone deacetylase |
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| Synonyms: | Hdac5 | Hdac5 protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34754.92 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_104809 |
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| Residue: | 328 |
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| Sequence: | MHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKL
LQQKLSVGKVLIVDWDIHHGNGTQQAFYDDPSVLYISLHRYDNGNFFPGSGAPEEVGGGP
GVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLG
GYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAV
LQQKPSINAVATLEKVIEIQSKHWSCVQRFATGLGCSLREAQTGEKEEAETVSAMALLSM
GAEQAQAAATQEHSPRPAEEPMEQEPAL
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| BDBM50475564 |
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| n/a |
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| Name | BDBM50475564 |
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| Synonyms: | CHEMBL381561 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO2S |
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| Mol. Mass. | 235.302 |
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| SMILES | ONC(=O)\C=C\C=C\CSc1ccccc1 |
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| Structure | 
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