| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily B member 2 |
|---|
| Ligand | BDBM50028124 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_423344 (CHEMBL855454) |
|---|
| IC50 | 524000±n/a nM |
|---|
| Citation |  Liu, H; Gao, ZB; Yao, Z; Zheng, S; Li, Y; Zhu, W; Tan, X; Luo, X; Shen, J; Chen, K; Hu, GY; Jiang, H Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay. J Med Chem50:83-93 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily B member 2 |
|---|
| Name: | Potassium voltage-gated channel subfamily B member 2 |
|---|
| Synonyms: | KCNB2 | KCNB2_HUMAN | Voltage-gated potassium channel subunit Kv2.2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 102555.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105708 |
|---|
| Residue: | 911 |
|---|
| Sequence: | MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTR
LGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFG
QELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLW
DLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVC
IAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVV
QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDE
DATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNF
SEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKD
SADDNHLSPSRWKWARKALSETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKL
EMLYNEITKTQPHSHPNPDCQEKPERPSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKST
SSIDSFTSCATDFTETERSPLPPPSASHLQMKFPTDLPGTEEHQRARGPPFLTLSREKGP
AARDGTLEYAPVDITVNLDASGSQCGLHSPLQSDNATDSPKSSLKGSNPLKSRSLKVNFK
ENRGSAPQTPPSTARPLPVTTADFSLTTPQHISTILLEETPSQGDRPLLGTEVSAPCQGP
SKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELPGAREEKQVDSSPNCFADKPSD
GRDPLREEGSVGSSSPQDTGHNCRQDIYHAVSEVKKDSSQEGCKMENHLFAPEIHSNPGD
TGYCPTRETSM
|
|
|
|---|
| BDBM50028124 |
|---|
| n/a |
|---|
| Name | BDBM50028124 |
|---|
| Synonyms: | 2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-methoxy-1H-indol-3-yl)ethanamine | 6-MeOT | CHEMBL337825 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H14N2O |
|---|
| Mol. Mass. | 190.2417 |
|---|
| SMILES | COc1ccc2c(CCN)c[nH]c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
