| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 11B1, mitochondrial |
|---|
| Ligand | BDBM50028171 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_192 |
|---|
| IC50 | 1530±n/a nM |
|---|
| Citation |  Hays, SJ; Tobes, MC; Gildersleeve, DL; Wieland, DM; Beierwaltes, WH Structure-activity relationship study of the inhibition of adrenal cortical 11 beta-hydroxylase by new metyrapone analogues. J Med Chem27:15-9 (1984) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 11B1, mitochondrial |
|---|
| Name: | Cytochrome P450 11B1, mitochondrial |
|---|
| Synonyms: | C11B1_BOVIN | CYP11B1 | Cytochrome P450 11B1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 57863.81 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1345884 |
|---|
| Residue: | 503 |
|---|
| Sequence: | MALWAKARVRMAGPWLSLHEARLLGTRGAAAPKAVLPFEAMPRCPGNKWMRMLQIWKEQS
SENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQADSHHPQRMILEPWLAYR
QARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNA
RGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFV
PRRLSRWMSTNMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMT
LDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQAVRQESLVAEARISENPQRAIT
ELPLLRAALKETLRLYPVGITLEREVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARP
ESYHPQRWLDRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKNFLVETLEQED
IKMVYRFILMPSTLPLFTFRAIQ
|
|
|
|---|
| BDBM50028171 |
|---|
| n/a |
|---|
| Name | BDBM50028171 |
|---|
| Synonyms: | 2-Methyl-1-phenyl-2-pyridin-3-yl-propan-1-ol | CHEMBL55378 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H17NO |
|---|
| Mol. Mass. | 227.3016 |
|---|
| SMILES | CC(C)(C(O)c1ccccc1)c1cccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
