| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50477812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_459966 (CHEMBL943094) |
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| Ki | 5012±n/a nM |
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| Citation |  Woods, CR; Hack, MD; Allison, BD; Phuong, VK; Rosen, MD; Morton, MF; Prendergast, CE; Barrett, TD; Shankley, NP; Rabinowitz, MH Synthesis and solid-phase purification of anthranilic sulfonamides as CCK-2 ligands. Bioorg Med Chem Lett17:6905-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | CCK-2 receptor | CCK-B receptor | CCK-BR | CCKBR | CCKRB | Cholecystokinin A | Cholecystokinin receptor | Cholecystokinin-2 Receptor | GASR_HUMAN | Gastrin/cholecystokinin type B receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48445.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Stable expression of human CCK-2 receptors in HEK 293 cells. |
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| Residue: | 447 |
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| Sequence: | MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
PDEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50477812 |
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| n/a |
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| Name | BDBM50477812 |
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| Synonyms: | CHEMBL400164 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21BrN2O6S2 |
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| Mol. Mass. | 517.414 |
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| SMILES | COC(=O)c1csc(c1OC)S(=O)(=O)Nc1cc(Br)ccc1C(=O)N1CCCCC1 |
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| Structure | 
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