| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
|---|
| Ligand | BDBM38949 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_476211 (CHEMBL923742) |
|---|
| IC50 | 1200±n/a nM |
|---|
| Citation |  Auld, DS; Southall, NT; Jadhav, A; Johnson, RL; Diller, DJ; Simeonov, A; Austin, CP; Inglese, J Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem51:2372-86 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Luciferin 4-monooxygenase |
|---|
| Name: | Luciferin 4-monooxygenase |
|---|
| Synonyms: | LUCI_PHOPY | Luciferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60747.46 |
|---|
| Organism: | Photinus pyralis |
|---|
| Description: | ChEMBL_938513 |
|---|
| Residue: | 550 |
|---|
| Sequence: | MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMS
VRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNI
SQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYD
FVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSV
VPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTL
IDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPG
AVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHS
GDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGEL
PAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILI
KAKKGGKSKL
|
|
|
|---|
| BDBM38949 |
|---|
| n/a |
|---|
| Name | BDBM38949 |
|---|
| Synonyms: | 4-methoxy-N-[(4-methyl-2-pyridyl)carbamoyl]benzamide | 4-methoxy-N-[(4-methylpyridin-2-yl)carbamoyl]benzamide | 4-methoxy-N-[[(4-methyl-2-pyridinyl)amino]-oxomethyl]benzamide | MLS000048748 | SMR000060445 | cid_1540545 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H15N3O3 |
|---|
| Mol. Mass. | 285.2979 |
|---|
| SMILES | COc1ccc(cc1)C(=O)NC(=O)Nc1cc(C)ccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
