| Reaction Details |
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 | Report a problem with these data |
| Target | Rho-related GTP-binding protein RhoC |
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| Ligand | BDBM50481368 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_604487 (CHEMBL1072732) |
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| IC50 | 36000±n/a nM |
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| Citation |  Evelyn, CR; Bell, JL; Ryu, JG; Wade, SM; Kocab, A; Harzdorf, NL; Showalter, HD; Neubig, RR; Larsen, SD Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423. Bioorg Med Chem Lett20:665-72 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Rho-related GTP-binding protein RhoC |
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| Name: | Rho-related GTP-binding protein RhoC |
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| Synonyms: | ARH9 | ARHC | RHOC | RHOC_HUMAN | Rho cDNA clone 9 | Rho-related GTP-binding protein RhoC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22006.13 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117031 |
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| Residue: | 193 |
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| Sequence: | MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
VRKNKRRRGCPIL
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| BDBM50481368 |
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| n/a |
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| Name | BDBM50481368 |
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| Synonyms: | CHEMBL591078 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12F6N2O3 |
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| Mol. Mass. | 406.2792 |
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| SMILES | FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)NOCC(=O)Nc1ccccc1 |
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| Structure | 
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