| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
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| Ligand | BDBM7457 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_644870 (CHEMBL1211147) |
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| IC50 | 1000±n/a nM |
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| Citation |  Gupta, AK; Saxena, S; Saxena, M Integrated ligand and structure based studies of flavonoids as fatty acid biosynthesis inhibitors of Plasmodium falciparum. Bioorg Med Chem Lett20:4779-81 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl-carrier protein reductase |
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| Name: | Enoyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49770.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_795989 |
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| Residue: | 432 |
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| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
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| BDBM7457 |
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| n/a |
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| Name | BDBM7457 |
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| Synonyms: | 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromone;dihydrate | CHEMBL31574 | Fisetin (14) | Fisetin, 15 | fisetin |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O6 |
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| Mol. Mass. | 286.2363 |
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| SMILES | Oc1ccc2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O |
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| Structure | 
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