| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50343682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_674284 (CHEMBL1274484) |
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| Ki | 0.46±n/a nM |
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| Citation |  Mohan, S; McAtamney, S; Haselhorst, T; von Itzstein, M; Pinto, BM Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles. J Med Chem53:7377-91 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | NA | NRAM_I33A0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49687.56 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1347422 |
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| Residue: | 453 |
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| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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| BDBM50343682 |
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| n/a |
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| Name | BDBM50343682 |
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| Synonyms: | ((1S,5R,6R)-6-acetamido-3-carboxy-5-(pentan-3-yloxy)cyclohex-2-enylamino)(amino)methaniminium 2,2,2-trifluoroacetate | (3S,4R,5R)-4-Acetamido-5-(1-ethylpropoxy)-3-guanidinocyclohex-1-ene-1-carboxylic Acid TrifluoroacetateSalt | CHEMBL1270126 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H26N4O4 |
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| Mol. Mass. | 326.3913 |
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| SMILES | [#6]-[#6]-[#6](-[#6]-[#6])-[#8]-[#6@@H]-1-[#6]-[#6](=[#6]-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6@H]-1-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O |r,c:8| |
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| Structure | 
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