| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin beta chain |
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| Ligand | BDBM50483308 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_700038 (CHEMBL1646630) |
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| Kd | 17900±n/a nM |
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| Citation |  Yamazaki, Y; Kido, Y; Hidaka, K; Yasui, H; Kiso, Y; Yakushiji, F; Hayashi, Y Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole. Bioorg Med Chem19:595-602 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin beta chain |
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| Name: | Tubulin beta chain |
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| Synonyms: | Beta-tubulin | TBB_PIG | Tubulin beta chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49840.26 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_105107 |
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| Residue: | 445 |
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| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEGEEDEA
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| BDBM50483308 |
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| n/a |
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| Name | BDBM50483308 |
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| Synonyms: | CHEMBL1643852 |
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| Type | Small organic molecule |
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| Emp. Form. | C53H67N11O8S |
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| Mol. Mass. | 1018.233 |
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| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)NCCCn3cc(CC(C)(C)c4ocnc4\C=c4/[nH]c(=O)\c(=C\c5cccc(c5)C(=O)c5ccccc5)[nH]c4=O)nn3)[C@@]1([H])NC(=O)N2 |r| |
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| Structure | 
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