| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 3 |
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| Ligand | BDBM35229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839168 (CHEMBL2077839) |
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| IC50 | 68000±n/a nM |
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| Citation |  Wu, X; Kekuda, R; Huang, W; Fei, YJ; Leibach, FH; Chen, J; Conway, SJ; Ganapathy, V Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain. J Biol Chem273:32776-86 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 3 |
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| Name: | Solute carrier family 22 member 3 |
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| Synonyms: | Oct3 | Organic cation transporter 3 | S22A3_RAT | Slc22a3 | Solute carrier family 22 member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61058.15 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_104125 |
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| Residue: | 551 |
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| Sequence: | MPTFDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALA
ERCAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEDTNTSSELSCDPLAAFPNRSAPLV
PCSGDWRYVETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIVY
LISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIV
IQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKAL
QILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVY
QGLVMRLGLIGGNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTA
FLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAP
FLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQLHQCGR
KKKTQVSTSNV
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| BDBM35229 |
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| n/a |
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| Name | BDBM35229 |
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| Synonyms: | 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine | 5-(gamma-methylaminopropyl)iminodibenzyl | CHEMBL72 | DESIPRAMINE HYDROCHLORIDE | DMI | Desipramin | Desipramine | Desmethylimipramine | N-(3-methylaminopropyl)iminobibenzyl | US9944618, Compound ID No. 174 | demethylimipramine | monodemethylimipramine | norimipramine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2 |
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| Mol. Mass. | 266.3807 |
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| SMILES | CNCCCN1c2ccccc2CCc2ccccc12 |
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| Structure | 
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