| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
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| Ligand | BDBM50350467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838502 (CHEMBL2078130) |
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| IC50 | >2000000±n/a nM |
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| Citation |  Jung, KY; Takeda, M; Shimoda, M; Narikawa, S; Tojo, A; Kim, DK; Chairoungdua, A; Choi, BK; Kusuhara, H; Sugiyama, Y; Sekine, T; Endou, H Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. Life Sci70:1861-74 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 6 |
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| Name: | Solute carrier family 22 member 6 |
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| Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60784.17 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_838479 |
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| Residue: | 551 |
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| Sequence: | MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL
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| BDBM50350467 |
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| n/a |
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| Name | BDBM50350467 |
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| Synonyms: | BL-S578 | CEFADROXIL | Cefadrops |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N3O5S |
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| Mol. Mass. | 363.388 |
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| SMILES | CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccc(O)cc1)C2=O)C(O)=O |r,t:1| |
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| Structure | 
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