| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM81939 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838285 (CHEMBL2076233) |
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| Ki | 2900±n/a nM |
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| Citation |  Zhang, L; Schaner, ME; Giacomini, KM Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther286:354-61 (1998) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 61154.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Adrenergic Alpha 0 HUMAN::O15245 |
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| Residue: | 554 |
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| Sequence: | MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
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| BDBM81939 |
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| n/a |
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| Name | BDBM81939 |
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| Synonyms: | CAS_52-53-9 | NSC_62969 | VERAPAMIL |
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| Type | Small organic molecule |
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| Emp. Form. | C27H38N2O4 |
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| Mol. Mass. | 454.6016 |
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| SMILES | COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC |
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| Structure | 
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