| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 5 |
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| Ligand | BDBM50485614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_836620 (CHEMBL2077361) |
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| IC50 | 64000000±n/a nM |
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| Citation |  Ganapathy, ME; Huang, W; Rajan, DP; Carter, AL; Sugawara, M; Iseki, K; Leibach, FH; Ganapathy, V beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. J Biol Chem275:1699-707 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 5 |
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| Name: | Solute carrier family 22 member 5 |
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| Synonyms: | High-affinity sodium-dependent carnitine cotransporter | OCTN2 | OCTN2_HUMAN | Organic cation/carnitine transporter 2 | SLC22A5 | Solute carrier family 22 member 5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62756.52 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_104634 |
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| Residue: | 557 |
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| Sequence: | MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSS
AWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
QDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQ
TGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYA
FGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKA
AKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFG
LSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLV
PPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYF
VYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTR
MLKDGQERPTILKSTAF
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| BDBM50485614 |
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| n/a |
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| Name | BDBM50485614 |
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| Synonyms: | Cefoselis |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N8O6S2 |
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| Mol. Mass. | 522.558 |
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| SMILES | [H][C@@]1(NC(=O)C(=N/OC)\c2csc(N)n2)C(=O)N2C(C([O-])=O)=C(C[n+]3ccc(N)n3CCO)CS[C@]12[H] |t:22| |
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| Structure | 
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