| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50029501 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_48475 (CHEMBL663037) |
|---|
| IC50 | 550±n/a nM |
|---|
| Citation |  Shuman, RT; Rothenberger, RB; Campbell, CS; Smith, GF; Gifford-Moore, DS; Paschal, JW; Gesellchen, PD Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitutions. J Med Chem38:4446-53 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54498.45 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1364435 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
|
|
|
|---|
| BDBM50029501 |
|---|
| n/a |
|---|
| Name | BDBM50029501 |
|---|
| Synonyms: | 5N-[4-amino(imino)methylamino-1-formyl-(1S)-butyl]-1-[(1R,4aS,8aS)-perhydro-1-isoquinolinylcarbonyl]-(5S)-dihydro-1H-5-pyrrolecarboxamide | CHEMBL136647 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H36N6O3 |
|---|
| Mol. Mass. | 420.5489 |
|---|
| SMILES | NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1NCC[C@@H]2CCCC[C@H]12)C=O |
|---|
| Structure | 
|
|---|
Search and Browse
