| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50029515 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48475 (CHEMBL663037) |
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| IC50 | 1300±n/a nM |
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| Citation |  Shuman, RT; Rothenberger, RB; Campbell, CS; Smith, GF; Gifford-Moore, DS; Paschal, JW; Gesellchen, PD Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitutions. J Med Chem38:4446-53 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54498.45 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1364435 |
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| Residue: | 492 |
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| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
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| BDBM50029515 |
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| n/a |
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| Name | BDBM50029515 |
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| Synonyms: | CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetidine-2-carboxylate-Arg-H |
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| Type | Small organic molecule |
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| Emp. Form. | C24H36N6O6 |
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| Mol. Mass. | 504.5792 |
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| SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
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| Structure | 
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