| Reaction Details |
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 | Report a problem with these data |
| Target | Proteinase-activated receptor 1 |
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| Ligand | BDBM50031382 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_209245 (CHEMBL814872) |
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| EC50 | 120±n/a nM |
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| Citation |  Feng, DM; Veber, DF; Connolly, TM; Condra, C; Tang, MJ; Nutt, RF Development of a potent thrombin receptor ligand. J Med Chem38:4125-30 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteinase-activated receptor 1 |
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| Name: | Proteinase-activated receptor 1 |
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| Synonyms: | CF2R | Coagulation factor II receptor | F2R | PAR-1 | PAR1 | PAR1_HUMAN | Proteinase activated receptor 1 | Proteinase-activated receptor 1 (PAR-1) | TR | Thrombin receptor | Thrombin receptor/ Proteinase-activated receptor 1(Par-1) |
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| Type: | Protein |
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| Mol. Mass.: | 47450.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25116 |
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| Residue: | 425 |
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| Sequence: | MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE
KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN
IMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTA
AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK
EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS
AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVS
SISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIY
KKLLT
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| BDBM50031382 |
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| n/a |
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| Name | BDBM50031382 |
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| Synonyms: | (S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-fluoro-phenyl)-propionylamino]-4-methyl-pentanoylamino}-4-methyl-pentanoylamino)-6-guanidino-hexanoic acid amide | CHEMBL337126 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H52FN9O5 |
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| Mol. Mass. | 649.8003 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCNC(N)=N)C(N)=O |
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| Structure | 
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