| Reaction Details |
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 | Report a problem with these data |
| Target | Angiotensin II receptor |
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| Ligand | BDBM50031962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36797 |
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| Ki | 0.29±n/a nM |
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| Citation |  Kiyama R; Honma T; Hayashi K; Ogawa M; Hara M; Fujimoto M; Fujishita T Novel angiotensin II receptor antagonists. Design, synthesis, and in vitro evaluation of dibenzo[a,d]cycloheptene and dibenzo[b,f]oxepin derivatives. Searching for bioisosteres of biphenylyltetrazole using a three-dimensional search technique. J Med Chem 38:2728-41 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Angiotensin II receptor |
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| Name: | Angiotensin II receptor |
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| Synonyms: | AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM50031962 |
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| n/a |
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| Name | BDBM50031962 |
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| Synonyms: | 3-(5,7-Dimethyl-2-propyl-imidazo[4,5-b]pyridin-3-ylmethyl)-11-(1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one | CHEMBL92950 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H25N7O |
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| Mol. Mass. | 475.5444 |
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| SMILES | CCCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1 |
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| Structure | 
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