| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Ligand | BDBM50033117 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_46332 (CHEMBL662623) |
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| Ki | 3600±n/a nM |
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| Citation |  Anderson, RC; Balestra, M; Bell, PA; Deems, RO; Fillers, WS; Foley, JE; Fraser, JD; Mann, WR; Rudin, M; Villhauer, EB Antidiabetic agents: a new class of reversible carnitine palmitoyltransferase I inhibitors. J Med Chem38:3448-50 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, liver isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Synonyms: | CPT I | CPT1-L | CPT1A_RAT | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform | Carnitine palmitoyltransferase 1A | Cpt-1 | Cpt1 | Cpt1a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88147.11 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_887445 |
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| Residue: | 773 |
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| Sequence: | MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPANPS
SWLIVVVGVISSMHAKVDPSLGMIAKISRTLDTTGRMSSQTKNIVSGVLFGTGLWVAVIM
TMRYSLKVLLSYHGWMFAEHGKMSRSTKIWMAMVKVLSGRKPMLYSFQTSLPRLPVPAVK
DTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGST
IPLCSAQWERLFNTSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELE
QQMQQILDDPSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTL
DESEQGYREEDPEASIDSYAKSLLHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPV
VGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGECQEVIDASLSSASLL
ANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACEKHQHLYRLAMTGAGIDRHLFCL
YVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGGFGPVADDGY
GVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLFGLTINSKK
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| BDBM50033117 |
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| n/a |
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| Name | BDBM50033117 |
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| Synonyms: | CHEMBL114113 | [3-Carboxy-2-(hydroxy-tetradecyloxy-phosphoryloxy)-propyl]-trimethyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C21H44NO6P |
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| Mol. Mass. | 437.5509 |
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| SMILES | CCCCCCCCCCCCCCOP([O-])(=O)O[C@H](CC(O)=O)C[N+](C)(C)C |
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| Structure | 
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