| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM50033684 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_40544 (CHEMBL652174) |
|---|
| IC50 | >20000±n/a nM |
|---|
| Citation |  Buynak, JD; Wu, K; Bachmann, B; Khasnis, D; Hua, L; Nguyen, HK; Carver, CL Synthesis and biological activity of 7-alkylidenecephems. J Med Chem38:1022-34 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | AMPC_ENTCL | ampC |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41306.67 |
|---|
| Organism: | Enterobacter cloacae |
|---|
| Description: | ChEMBL_40258 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHY
YTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQ
WQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGA
LAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQA
YGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEA
NTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLA
NTSYPNPARVEAAYHILEALQ
|
|
|
|---|
| BDBM50033684 |
|---|
| n/a |
|---|
| Name | BDBM50033684 |
|---|
| Synonyms: | CHEMBL269657 | Sodium; (R)-3-acetoxymethyl-7-[1-bromo-meth-(E)-ylidene]-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H9BrNO7S |
|---|
| Mol. Mass. | 379.161 |
|---|
| SMILES | CC(=O)OCC1=C(N2[C@@H](\C(=C\Br)C2=O)S(=O)(=O)C1)C([O-])=O |t:5| |
|---|
| Structure | 
|
|---|
Search and Browse
