Ki Summary

Reaction Details

Report a problem with these data

Target

Muscarinic receptor M1

Ligand

BDBM50034872

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_138130 (CHEMBL872660)

0.20±n/a nM

Citation

Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem38:1711-9 (1995) [PubMed]

More Info.:

Get all data from this article, Assay Method

Muscarinic receptor M1

Name:

Muscarinic receptor M1

Synonyms:

Muscarinic acetylcholine receptor M1

Type:

PROTEIN

Mol. Mass.:

15022.43

Organism:

Bos taurus

Description:

ChEMBL_140161

Residue:

139

Sequence:

ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYS
WKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKG
RERAGKGQKPRGKEQLAKR

BDBM50034872

n/a

Name

BDBM50034872

Synonyms:

(S)-[4-(3-Fluoro-propyl)-phenyl]-hydroxy-phenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | CHEMBL296895

Type

Small organic molecule

Emp. Form.

C24H28FNO3

Mol. Mass.

397.4824

SMILES

O[C@@](C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccc(CCCF)cc1 |wU:1.1,wD:1.0,THB:4:5:9.8:11.12,(6.11,-5.14,;5.36,-6.48,;6.88,-7.04,;7.13,-8.54,;8.06,-6.06,;9.51,-6.59,;10.28,-5.37,;11.98,-4.6,;13.54,-5.53,;12.74,-6.67,;11.14,-5.72,;11.14,-4.34,;11.98,-3.53,;4.02,-5.71,;4.02,-4.15,;2.67,-3.38,;1.36,-4.17,;1.36,-5.71,;2.67,-6.48,;4.57,-7.81,;5.3,-9.12,;4.53,-10.44,;2.99,-10.44,;2.19,-11.77,;.65,-11.75,;-.12,-13.07,;-1.66,-13.06,;2.22,-9.09,;3.03,-7.77,)|

Structure