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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M2 | ||
| Ligand | BDBM50034872 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_138162 (CHEMBL748226) | ||
| Ki | 0.38±n/a nM | ||
| Citation |  Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem38:1711-9 (1995) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M2 | |||
| Name: | Muscarinic acetylcholine receptor M2 | ||
| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 51555.53 | ||
| Organism: | RAT | ||
| Description: | P10980 | ||
| Residue: | 466 | ||
| Sequence: |
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| BDBM50034872 | |||
| n/a | |||
| Name | BDBM50034872 | ||
| Synonyms: | (S)-[4-(3-Fluoro-propyl)-phenyl]-hydroxy-phenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | CHEMBL296895 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H28FNO3 | ||
| Mol. Mass. | 397.4824 | ||
| SMILES | O[C@@](C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccc(CCCF)cc1 |wU:1.1,wD:1.0,THB:4:5:9.8:11.12,(6.11,-5.14,;5.36,-6.48,;6.88,-7.04,;7.13,-8.54,;8.06,-6.06,;9.51,-6.59,;10.28,-5.37,;11.98,-4.6,;13.54,-5.53,;12.74,-6.67,;11.14,-5.72,;11.14,-4.34,;11.98,-3.53,;4.02,-5.71,;4.02,-4.15,;2.67,-3.38,;1.36,-4.17,;1.36,-5.71,;2.67,-6.48,;4.57,-7.81,;5.3,-9.12,;4.53,-10.44,;2.99,-10.44,;2.19,-11.77,;.65,-11.75,;-.12,-13.07,;-1.66,-13.06,;2.22,-9.09,;3.03,-7.77,)| | ||
| Structure | 
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