| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50036842 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_37537 (CHEMBL647619) |
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| Ki | 850±n/a nM |
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| Citation |  Macchia, B; Balsamo, A; Breschi, MC; Chiellini, G; Macchia, M; Martinelli, A; Martini, C; Nardini, C; Nencetti, S; Rossello, A The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists. J Med Chem37:1518-25 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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| BDBM50036842 |
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| n/a |
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| Name | BDBM50036842 |
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| Synonyms: | 3-tert-Butylamino-2-hydroxy-propionaldehyde O-propyl-oxime; compound with (E)-but-2-enedioic acid | CHEMBL39706 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H22N2O2 |
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| Mol. Mass. | 202.2939 |
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| SMILES | CCCO\N=C\C(O)CNC(C)(C)C |
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| Structure | 
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