| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50036839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39169 (CHEMBL654466) |
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| IC50 | 12303±n/a nM |
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| Citation |  Macchia, B; Balsamo, A; Breschi, MC; Chiellini, G; Macchia, M; Martinelli, A; Martini, C; Nardini, C; Nencetti, S; Rossello, A The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists. J Med Chem37:1518-25 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50540.48 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
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| Residue: | 467 |
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| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
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| BDBM50036839 |
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| n/a |
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| Name | BDBM50036839 |
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| Synonyms: | 2-Hydroxy-3-isopropylamino-propionaldehyde O-ethyl-oxime; compound with (E)-but-2-enedioic acid | CHEMBL39682 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H18N2O2 |
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| Mol. Mass. | 174.2407 |
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| SMILES | CCO\N=C\C(O)CNC(C)C |
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| Structure | 
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