| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit rho-1 |
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| Ligand | BDBM50492303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_967444 (CHEMBL2401234) |
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| IC50 | 6600±n/a nM |
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| Citation |  Locock, KE; Yamamoto, I; Tran, P; Hanrahan, JR; Chebib, M; Johnston, GA; Allan, RD ?-aminobutyric acid(C) (GABAC) selective antagonists derived from the bioisosteric modification of 4-aminocyclopent-1-enecarboxylic acid: amides and hydroxamates. J Med Chem56:5626-30 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit rho-1 |
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| Name: | Gamma-aminobutyric acid receptor subunit rho-1 |
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| Synonyms: | GABA receptor rho-1 subunit | GABA-C receptor | GABRR1 | GBRR1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55892.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456653 |
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| Residue: | 479 |
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| Sequence: | MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI
LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM
TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV
QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD
ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW
VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL
EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP
DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
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| BDBM50492303 |
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| n/a |
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| Name | BDBM50492303 |
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| Synonyms: | CHEMBL2398121 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H9NO2 |
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| Mol. Mass. | 127.1412 |
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| SMILES | NC1CC=C(C1)C(O)=O |c:3| |
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| Structure | 
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