| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
|---|
| Ligand | BDBM50492425 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_970263 (CHEMBL2406666) |
|---|
| Ki | 117±n/a nM |
|---|
| Citation |  Waszkielewicz, AM; Gunia, A; Szkaradek, N; Pytka, K; Siwek, A; Sata?a, G; Bojarski, AJ; Szneler, E; Marona, H Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. Bioorg Med Chem Lett23:4419-23 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1A |
|---|
| Name: | 5-hydroxytryptamine receptor 1A |
|---|
| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46122.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 422 |
|---|
| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
|
|
|
|---|
| BDBM50492425 |
|---|
| n/a |
|---|
| Name | BDBM50492425 |
|---|
| Synonyms: | CHEMBL2401935 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H25ClN2O3 |
|---|
| Mol. Mass. | 436.931 |
|---|
| SMILES | Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
