| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
|---|
| Ligand | BDBM50492465 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_969519 (CHEMBL2406030) |
|---|
| Ki | 0.960000±n/a nM |
|---|
| Citation |  Güzel-Akdemir, Ö; Akdemir, A; Pan, P; Vermelho, AB; Parkkila, S; Scozzafava, A; Capasso, C; Supuran, CT A class of sulfonamides with strong inhibitory action against the ?-carbonic anhydrase from Trypanosoma cruzi. J Med Chem56:5773-81 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 2 |
|---|
| Name: | Carbonic anhydrase 2 |
|---|
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29250.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00918 |
|---|
| Residue: | 260 |
|---|
| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
|
|
|
|---|
| BDBM50492465 |
|---|
| n/a |
|---|
| Name | BDBM50492465 |
|---|
| Synonyms: | CHEMBL2402767 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H13BrN2O3S |
|---|
| Mol. Mass. | 369.234 |
|---|
| SMILES | NS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2Br)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
