| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50010591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58512 (CHEMBL672007) |
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| Ki | 200±n/a nM |
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| Citation |  Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors. J Med Chem37:2686-96 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50010591 |
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| n/a |
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| Name | BDBM50010591 |
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| Synonyms: | 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | CHEMBL73538 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4 |
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| Mol. Mass. | 292.3782 |
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| SMILES | CN1CCN(CC1)C1=Nc2ccccc2Nc2ccccc12 |t:8| |
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| Structure | 
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