| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50040128 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_223426 (CHEMBL844036) |
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| IC50 | 9.7±n/a nM |
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| Citation |  Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs. J Med Chem36:750-7 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
|
|
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| BDBM50040128 |
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| n/a |
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| Name | BDBM50040128 |
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| Synonyms: | CHEMBL384566 | Tyr-(D-ala)-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) |
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| Type | Small organic molecule |
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| Emp. Form. | C58H90N20O13S2 |
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| Mol. Mass. | 1339.591 |
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| SMILES | CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |
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| Structure | 
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