| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50040123 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_223435 (CHEMBL845237) |
|---|
| IC50 | 28.93±n/a nM |
|---|
| Citation |  Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs. J Med Chem36:750-7 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40577.25 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P32300 |
|---|
| Residue: | 372 |
|---|
| Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50040123 |
|---|
| n/a |
|---|
| Name | BDBM50040123 |
|---|
| Synonyms: | CHEMBL438223 | HTry-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysOH | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys | [D-Pro-10]Dyn A-(1-11) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C63H103N21O13 |
|---|
| Mol. Mass. | 1362.6248 |
|---|
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
