| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50040138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_59311 (CHEMBL666964) |
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| IC50 | 3430±n/a nM |
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| Citation |  Tupper, DE; Pullar, IA; Clemens, JA; Fairhurst, J; Risius, FC; Timms, GH; Wedley, S Synthesis and dopamine antagonist activity of 2-thioether derivatives of the ergoline ring system. J Med Chem36:912-8 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50698.79 |
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| Organism: | BOVINE |
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| Description: | P20288 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
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| BDBM50040138 |
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| n/a |
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| Name | BDBM50040138 |
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| Synonyms: | 9-Methyl-5-methylsulfanyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline | CHEMBL366850 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2S |
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| Mol. Mass. | 270.393 |
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| SMILES | CSc1[nH]c2cccc3[C@H]4C=C(C)CN[C@@H]4Cc1c23 |t:10| |
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| Structure | 
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