| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Chymotrypsin-C |
|---|
| Ligand | BDBM50036127 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_49623 (CHEMBL660461) |
|---|
| Ki | 55±n/a nM |
|---|
| Citation |  Brown, FJ; Andisik, DW; Bernstein, PR; Bryant, CB; Ceccarelli, C; Damewood, JR; Edwards, PD; Earley, RA; Feeney, S; Green, RC Design of orally active, non-peptidic inhibitors of human leukocyte elastase. J Med Chem37:1259-61 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Chymotrypsin-C |
|---|
| Name: | Chymotrypsin-C |
|---|
| Synonyms: | CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29487.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99895 |
|---|
| Residue: | 268 |
|---|
| Sequence: | MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
RGCNTRKKPVVYTRVSAYIDWINEKMQL
|
|
|
|---|
| BDBM50036127 |
|---|
| n/a |
|---|
| Name | BDBM50036127 |
|---|
| Synonyms: | CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid benzyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H26F3N3O5 |
|---|
| Mol. Mass. | 529.5076 |
|---|
| SMILES | CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
