| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50494905 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1281575 (CHEMBL3102260) |
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| IC50 | 4.3±n/a nM |
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| Citation |  Iyidogan, P; Sullivan, TJ; Chordia, MD; Frey, KM; Anderson, KS Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase. ACS Med Chem Lett4:1183-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50494905 |
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| n/a |
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| Name | BDBM50494905 |
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| Synonyms: | CHEMBL3099595 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H44N7O9P |
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| Mol. Mass. | 785.7819 |
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| SMILES | Cc1cc(cc(C)c1Oc1ccnc(Nc2ccc(cc2)C#N)n1)C#CCCCCCCCC(=O)NCc1cn([C@H]2C[C@H](O)[C@@H](COP(O)=O)O2)c(=O)[nH]c1=O |r| |
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| Structure | 
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