| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A1 |
|---|
| Ligand | BDBM50011216 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_29299 (CHEMBL640360) |
|---|
| Ki | 32.6±n/a nM |
|---|
| Citation |  Peet, NP; Lentz, NL; Dudley, MW; Ogden, AM; McCarty, DR; Racke, MM Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists. J Med Chem36:4015-20 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A1 |
|---|
| Name: | Adenosine receptor A1 |
|---|
| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36704.13 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 326 |
|---|
| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
|
|
|
|---|
| BDBM50011216 |
|---|
| n/a |
|---|
| Name | BDBM50011216 |
|---|
| Synonyms: | 1-Methyl-8-(1-methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL337073 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H26N4O2 |
|---|
| Mol. Mass. | 354.446 |
|---|
| SMILES | CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
