| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50496120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1294037 (CHEMBL3122548) |
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| Ki | 62±n/a nM |
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| Citation |  Sagnes, C; Fournet, G; Satala, G; Bojarski, AJ; Joseph, B New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies. Eur J Med Chem75:159-68 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46445.29 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Binding assays were performed using rat hippocampal membranes. |
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| Residue: | 422 |
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| Sequence: | MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT
SLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGN
SKEHLPLPSESGSNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RR
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| BDBM50496120 |
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| n/a |
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| Name | BDBM50496120 |
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| Synonyms: | CHEMBL3121413 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N2O4 |
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| Mol. Mass. | 380.437 |
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| SMILES | OC(=O)\C=C\C(O)=O.CN(C)CCc1cn(-c2ccccc2)c2ccccc12 |
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| Structure | 
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