| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50496207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1295476 (CHEMBL3131474) |
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| IC50 | 340±n/a nM |
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| Citation |  Grienke, U; Braun, H; Seidel, N; Kirchmair, J; Richter, M; Krumbholz, A; von Grafenstein, S; Liedl, KR; Schmidtke, M; Rollinger, JM Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod77:563-70 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | NA | NRAM_I33A0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49687.56 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1347422 |
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| Residue: | 453 |
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| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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| BDBM50496207 |
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| n/a |
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| Name | BDBM50496207 |
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| Synonyms: | CHEMBL3125439 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H35NO14 |
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| Mol. Mass. | 693.6507 |
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| SMILES | [H][C@@]1(O[C@H]2OC[C@@](O)(COC(=O)c3c[nH]c4ccccc34)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1 |r| |
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| Structure | 
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