| Reaction Details |
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 | Report a problem with these data |
| Target | Lethal(3)malignant brain tumor-like protein 1 |
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| Ligand | BDBM50341828 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1300219 (CHEMBL3136683) |
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| IC50 | 21000±n/a nM |
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| Citation |  Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm4:1501-1507 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lethal(3)malignant brain tumor-like protein 1 |
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| Name: | Lethal(3)malignant brain tumor-like protein 1 |
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| Synonyms: | H-l(3)mbt | H-l(3)mbt protein | KIAA0681 | L(3)mbt protein homolog | L(3)mbt-like | L3MBT | L3MBTL | L3MBTL1 | LMBL1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 92284.44 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_103624 |
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| Residue: | 840 |
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| Sequence: | MHLVAGDSPGSGPHLPATAFIIPASSATLGLPSSALDVSCFPREPIHVGAPEQVAGCEPV
SATVLPQLSAGPASSSTSTVRLLEWTEAAAPPPGGGLRFRISEYKPLNMAGVEQPPSPEL
RQEGVTEYEDGGAPAGDGEAGPQQAEDHPQNPPEDPNQDPPEDDSTCQCQACGPHQAAGP
DLGSSNDGCPQLFQERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAMEKQ
EEGKDPEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVT
HNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHP
AGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLE
AVDRMNPSLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTP
PQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVE
DVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASPGGCP
PLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKAEL
SDSEASARKKNLSGFSPRKKPRHHGRIGRPPKYRKIPQEDFQTLTPDVVHQSLFMSALSA
HPDRSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFGFVQTLTGCEDQARLFKDEARIV
RVTHVSGKTLVWTVAQLGDLVCSDHLQEGKGILETGVHSLLCSLPTHLLAKLSFASDSQY
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| BDBM50341828 |
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| n/a |
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| Name | BDBM50341828 |
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| Synonyms: | 3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbonyl]pyridine | 5-Bromo-N-(4-(pyrrolidinyl)piperidinyl)nicotinamide | CHEMBL1235119 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20BrN3O |
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| Mol. Mass. | 338.243 |
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| SMILES | Brc1cncc(c1)C(=O)N1CCC(CC1)N1CCCC1 |
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| Structure | 
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